Vialess heterogeneous skin patch for multimodal monitoring and stimulation

Abstract System-level wearable electronics require to be flexible to ensure conformal contact with the skin, but they Roll Neck Sweaters also need to integrate rigid and bulky functional components to achieve system-level functionality.As one of integration methods, folding integration offers simplified processing and enhanced functionality through rigid-soft region separation, but so far, it has mainly been applied to modality of electrical sensing and stimulation.This paper introduces a vialess heterogeneous skin patch with multi modalities that separates the soft region and strain-robust region through folded structure.Our system includes electrical and optical modalities for hemodynamic and cardiovascular monitoring, and a force-electrically driven micropump for drug delivery.

Each modality is demonstrated through on-demand drug delivery, flexible waveguide-based PPG monitoring, and ECG and body movement monitoring.Wireless data transmission and real-time measurement validate the feedback operation for multi-modalities.This engineered closed-loop platform offers the possibility for broad applications, including cardiovascular monitoring and Phone Accessories chronic disease management.

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